A 30-year-old male consulted us for the treatment of Genital Herpes. He described that the complaint had become recurrent and he used to get new eruptions periodically even before the old ones healed. He described that the eruptions initially were painless but after two or three weeks, he started experiencing severe pain in the eruptions. Even after proper treatment, the old ones refused to heal and started developing ulcers instead. Currently he had intolerable itching around the eruptions with unbearable burning pain. The itching over the eruptions was worse in the night and thus he was sleep deprived as well. The eruptions around the genitals appeared swollen and were fiery red in colour. The old eruptions were covered with thick scabs and little ulceration. His complaints increased in the night and on touch. He was better by uncovering the parts. He was prescribed the Homoeopathic remedy Mezerum. He started showing improvement and the pain as well as itching reduced considerably within a month of initiation of treatment. His eruptions started healing and the recurrence stopped completely by the end of five months of treatment.