- Genetic disorders of blood vessels
- Family History: One is more likely to get Trigeminal Neuralgia if a family member has the same.
- Abnormality of veins or arteries due to any disease may irritate or damage the nerve.
- Age: People above 50 years are at risk more than others
- Sex: Women are more likely to suffer from Trigeminal neuralgia the ratio of women to men being 3:2.
- In Multiple sclerosis the fatty substance called myelin that surrounds and insulates nerve fibers gets damaged and hardened which leads to Trigeminal neuralgia.