- Cosmetically unattractive: This is the prime complication of ganglion especially if present on visible body part may look ugly.
- Restriction of joint mobility: Ganglion may put pressure on nerve causing limitation of joint movement.
- Pain: Ganglion may put pressure on nerve causing severe pain.
- Stiffness: Ganglion may cause pain on moving joint, as a result patient may avoid joint movement. Prolonged immobilization of joint may cause stiffness.
- Recurrence: Recurrence rate is quite high especially if aspiration is used. While surgical excision also may lead to recurrence in high number of cases.
- Scar formation: It is usually common after surgery.
- Infection: Rarely the fluid inside the Ganglion may get infected and cause severe bone infections.