- Pre existing diseases: Cellulitis can develop in areas where there are already some skin infections like Athlete's foot, Impetigo, Eczema, Psoriasis, Skin rash, Boils, chicken pox, shingles etc.
- Oedema: Cellulitis can develop in areas of oedema or swelling like in chronic leg oedema.
- Diabetes: Cellulitis is very common in people with uncontrolled Diabetes, due to favoured proliferation of bacteria in high blood sugar.
- Poor Immunity: People who have low immunity like patients of AIDS or Cancer patients who are on chemotherapy are also likely to be at higher risk of developing Cellulitis.
- Circulatory problems: Those who have compromised blood or lymphatic flow like in pregnancy, obesity, surgery, venous insufficiency, varicose veins are at higher risk of Cellulitis.
- Morbid Obesity and old age: Cellulitis is very common in obese individuals and also its risk increases after middle age. It is also common in smokers.
- Poor sanitation: Crowded areas and poor sanitation seen in camps, slums, and homeless centres are more likely to increase chance of Cellulitis. Also they are associated with poor immunity.