Smoking: Smoking increases risk of Peptic Ulcers.
Drinking alcohol: Alcohol can irritate and erode mucous lining of stomach. It also increases the amount of stomach acid that is produced.
Non-steroidal anti-inflammatory drugs (NSAIDs): Use of NSAIDs has shown to increase risk of gastrointestinal bleeding and perforation.
Past and Family history: Past and Family history of Ulcers increases risk of ulceration.
Physical stress: Physical stress caused by injury like major trauma, surgery or serious illness.