- Color of skin and racial variation - Individuals with darker pigmentation/complexion, people of African or Asian descents are more likely to develop Keloids then people with lighter skin.
- Age- The average age of onset is 10-30 years. Persons older than 65 years rarely develop keloids. However, in rare cases, Keloids have been observed in infants and adults over the age of 70 also.
- Gender - Keloids are equally common in both women and men. Although recently, more keloids are developing more in women because of a greater cosmetic concern or a greater degree of earlobe and body piercing among women.
- Tuberculosis- Patients with Tuberculosis are more prone to develop Keloids.
- Individual factors- some persons have a tendency to form Keloids which is known as a keloid diathesis.
- Hormonal influence – Repeated pregnancies may possibly lead to Keloid formation.
- Keloid may follow bacterial or viral infections. Pimple, smallpox, and herpes varicella-zoster can lead to Keloid.