• Genetics: ODD can be due to genetic causes leading to some neurobiological changes in brain.
• Way of Upbringing: Lack of proper parental supervision, discipline, child abuse or child neglect can also cause ODD in children.
• Emotional factor: Child who has witnessed parental separation or divorce or constant fights between parents can also develop ODD. Those kids whose parents are addicted to any substance (substance abuse) are also at risk.
• Prenatal factors: Certain pregnancy and birth problems are also linked with ODD. Malnutrition, protein deficiency, lead poisoning, use of alcohol or nicotine by mother during pregnancy are also linked with ODD, although, it is not proved.